Login / Signup

Cardiomyocyte LGR6 alleviates ferroptosis in diabetic cardiomyopathy via regulating mitochondrial biogenesis.

Mengmeng ZhaoZican ShenZihui ZhengYao XuJishou ZhangJianfang LiuShanshan PengJun WanJuan-Juan QinMenglong Wang
Published in: Metabolism: clinical and experimental (2024)
We identified a previously undescribed signaling pathway of the LGR6-STAT3-Pgc1a axis that plays a critical role in ferroptosis and mitochondrial disorders during diabetic cardiomyopathy and provides an option for treatment of diabetic hearts.
Keyphrases