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Current ideas about the roles of rapid eye movement and non-rapid eye movement sleep in brain development.

Marit S KnoopEline R de GrootJeroen Dudink
Published in: Acta paediatrica (Oslo, Norway : 1992) (2020)
Understanding the links between sleep and brain development is important, as rapid eye movement (REM) sleep and non-REM (NREM) sleep seem to contribute to different aspects of brain maturation. If children have sleep problems, REM sleep and NREM sleep are likely to have different consequences for their developing brain, depending on their age. We highlight important discoveries from human and animal research on the role sleep plays in brain development. A hypothetical model is presented to explain the dynamic relationship of REM sleep and NREM sleep with different processes of brain maturation, with implications for current neonatal care and future research.
Keyphrases
  • sleep quality
  • physical activity
  • resting state
  • white matter
  • healthcare
  • functional connectivity
  • endothelial cells
  • young adults
  • palliative care
  • induced pluripotent stem cells