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Extracellular arginine availability modulates eIF2α O-GlcNAcylation and heme oxygenase 1 translation for cellular homeostasis.

Yu-Wen HungChing OuyangXiaoli PingYue QiYi-Chang WangHsing-Jien KungDavid K Ann
Published in: Journal of biomedical science (2023)
Overall, this study provides new insights into how ArgS fine-tunes the control of translation initiation and antioxidant defense through eIF2α O-GlcNAcylation, which has potential biological and clinical implications.
Keyphrases
  • nitric oxide
  • air pollution
  • oxidative stress
  • anti inflammatory
  • antibiotic resistance genes
  • climate change
  • amino acid
  • microbial community
  • human health