Novel Derivatives of Tetrahydrobenzo (g) Imidazo[α-1,2] Quinoline Induce Apoptosis Via ROS Production in the Glioblastoma Multiforme Cells, U-87MG.

Fatemeh Mostafavi HosseiniMaryam AshourpourSalman TaheriMasoumeh Tavakoli YarakiSiamak Salami Zahra ShahsavariFaranak Kazerouni

Published in: Asian Pacific journal of cancer prevention : APJCP (2022)

Our data provide insights into the potent anticancer effects of the 5c-derivative of tetrahydrobenzo(g)imidazo[α-1,2]quinolone on GBM cells via the caspase-dependent apoptotic pathway, which may merit further attention.

Keyphrases

cell cycle arrest
cell death
induced apoptosis
endoplasmic reticulum stress
oxidative stress
pi k akt
electronic health record
working memory
machine learning
big data
molecular docking
cell proliferation
molecular dynamics simulations
data analysis