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Cutaneous Events Associated with Immunotherapy of Melanoma: A Review.

Lorenza BurziAurora Maria AlessandriniPietro QuaglinoBianca Maria PiracciniEmi DikaSimone Ribero
Published in: Journal of clinical medicine (2021)
Immunotherapy with checkpoint inhibitors significantly improves the outcome for stage III and IV melanoma. Cutaneous adverse events during treatment are often reported. We herein aim to review the principal pigmentation changes induced by immune check-point inhibitors: the appearance of vitiligo, the Sutton phenomenon, melanosis and hair and nail toxicities.
Keyphrases
  • dna damage
  • skin cancer
  • cell cycle
  • oxidative stress
  • cell proliferation