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Concordance in Oncogenic Alterations Between the Primary Tumor and Advanced Disease: Insights Into the Heterogeneity of Intrahepatic Cholangiocarcinoma.

Sarah M McIntyreWilliam A PrestonHenry S WalchJeremy SharibRitika KundraCarlie SigelMichael E LidskyPeter J AllenMichael A MorseWei ChenAndrea CercekJames J HardingGhassan K Abou-AlfaEileen M O'ReillyWungki ParkVinod P BalachandranJeffrey DrebinKevin C SoaresAlice C WeiT Peter KinghamMichael I D'AngelicaChristine A Iacobuzio-DonahueWilliam R Jarnagin
Published in: JCO precision oncology (2024)
The results reflect a high degree of heterogeneity in ICCA and argue for reassessment of the dominant driver mutations with change in disease status.
Keyphrases
  • single cell
  • transcription factor