Quantitative Analysis of the MGMT Methylation Status of Glioblastomas in Light of the 2021 WHO Classification.

Levin HäniMonika KopcicMattia BrancaAlessa SchützMichael MurekNicole SöllErik VassellaAndreas RaabeEkkehard HewerPhilippe Schucht

Published in: Cancers (2022)

promoter region than with <16% methylation. Survival with tumors with 1-15% methylation is similar to with unmethylated tumors. Above 16% methylation, we found no additional benefit with increasing methylation.

Keyphrases

dna methylation
genome wide
gene expression
machine learning
transcription factor
free survival