Disrupted hypothalamic transcriptomics and proteomics in a mouse model of type 2 diabetes exposed to recurrent hypoglycaemia.

Judit Castillo-Armengol Flavia Marzetta Ana Rodriguez Sanchez-ArchidonaChristian FledeliusMark L Evans Alison D McNeilly Rory J McCrimmon Mark Ibberson Bernard Thorens

Published in: Diabetologia (2023)

The transcriptomic dataset is available via the GEO ( http://www.ncbi.nlm.nih.gov/geo/ ), using the accession no. GSE226277. The proteomic dataset is available via the ProteomeXchange data repository ( http://www.proteomexchange.org ), using the accession no. PXD040183.

Keyphrases

type diabetes
mouse model
single cell
label free
rna seq
glycemic control
mass spectrometry
electronic health record
cardiovascular disease
big data
insulin resistance
resting state
metabolic syndrome
functional connectivity
machine learning
data analysis
skeletal muscle
weight loss
deep learning