Brief Report: Dolutegravir Plasma Protein Binding and Unbound Concentrations During Pregnancy and Postpartum.

Jeremiah D MomperMina NikanjamBrookie M BestMark MirochnickEdmund V CapparelliTim Roy Cressey

Published in: Journal of acquired immune deficiency syndromes (1999) (2023)

Lower total DTG plasma concentrations during pregnancy coincide with temporal decreases in DTG protein binding, resulting in comparable unbound DTG concentrations during the 3T and PP.

Keyphrases

binding protein
protein protein
amino acid
dna binding
antiretroviral therapy
small molecule