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Aging influence on pulmonary and systemic inflammation and neural metabolomics arising from pulmonary multi-walled carbon nanotube exposure in apolipoprotein E-deficient and C57BL/6 female mice.

Tamara L YoungDavid ScieszkaJessica G BegaySelita N LucasGuy HerbertKatherine E ZychowskiRussell HunterRaul SalazarAndrew K OttensAaron ErdelyHaiwei GuMatthew J Campen
Published in: Inhalation toxicology (2022)
Age influences the pulmonary and neurological responses to short-term MWCNT exposure. However, with only the model of moderate aging (15 months) in this study, the responses appeared modest compared to inhaled toxicant impacts in more advanced aging models.
Keyphrases
  • pulmonary hypertension
  • carbon nanotubes
  • cystic fibrosis
  • high intensity
  • metabolic syndrome
  • adipose tissue
  • skeletal muscle
  • brain injury
  • blood brain barrier
  • insulin resistance