Quantitative detection of methylated SOCS-1 in schizophrenia and bipolar disorder considering SOCS-1 -1478CA/del polymorphism and clinical parameters.

Hasan Mervan Aytac Sacide Pehlivan Mustafa Pehlivan Yasemin Oyaci

Published in: Irish journal of medical science (2022)

In summary, the methylated SOCS-1 quantity in DNA samples of SCZ and BD patients were significantly lower than in control samples. Whereas the SOCS-1 -1478CA/del polymorphism was not related to SCZ, it may be associated with the BD.

Keyphrases

bipolar disorder
end stage renal disease
major depressive disorder
ejection fraction
chronic kidney disease
newly diagnosed
high resolution
single molecule
protein kinase
cell free
patient reported
drug induced