Diagnostic accuracy of immunofluorescence versus immunoperoxidase staining to distinguish immune complex-mediated glomerulonephritis and C3 dominant glomerulopathy.
Yassine BouatouJesper KersMarie S N Chevalier-FlorquinNike ClaessenTri Q NguyenJeffrey DammanHenrique ProençaJoris J T H RoelofsSandrine FlorquinPublished in: Histopathology (2017)
The diagnosis of ICGN versus C3GN depends on the immunochemical technique used. Also, the use of C4d failed to discriminate ICGN from C3G in our study. Further validation studies are required to avoid misdiagnosis based on kidney biopsy.