Effects Mediated by Dimethyl Fumarate on In Vitro Oligodendrocytes: Implications in Multiple Sclerosis.

Claudia GuerrieroGiulia PuliattiTamara Di MarinoAda Maria Tata

Published in: International journal of molecular sciences (2022)

The results obtained confirm that DMF has anti-inflammatory and antioxidant effects also on Oli neu cells. Interestingly, it appears to promote the OLCs differentiation towards mature and potentially myelinating cells.

Keyphrases

induced apoptosis
multiple sclerosis
anti inflammatory
cell cycle arrest
oxidative stress
signaling pathway
white matter