Exosome-Delivered c-Met siRNA Could Reverse Chemoresistance to Cisplatin in Gastric Cancer.

Qiumo ZhangHaiyang ZhangTao NingDongying LiuTing DengRui LiuMing BaiKegan ZhuJialu LiQian FanGuoguang YingYi Ba

Published in: International journal of nanomedicine (2020)

Our results indicate that exo-si-c-Met can inhibit the invasion and migration of gastric cancer cells and promote apoptosis in vitro and inhibit tumor growth in vivo, reversing the resistance to cisplatin in gastric cancer.

Keyphrases

tyrosine kinase
oxidative stress
endoplasmic reticulum stress
cell migration
cell cycle arrest
cancer therapy
room temperature
cell proliferation
hyaluronic acid