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Discovery proteomics reveals potential protein signature associated with malignant phenotype acquisition in pleomorphic adenoma.

Reydson Alcides de Lima SouzaJoão Figueira ScariniLuccas LavarezeCarolina Emerick DA Silva RangelLívia Ramalho CrescencioRomênia Ramos DominguesAdriana Franco Paes LemeBruno Augusto Linhares Almeida MarizDébora Campanella BastosRenato Assis MachadoAlfio José TincaniAndré Del NegroCarlos Takahiro ChoneLuiz Paulo KowalskiFernanda Viviane MarianoAlbina Messias de Almeida Milani AltemaniFernanda Viviane Mariano
Published in: Oral diseases (2021)
In this work, we demonstrated the comparative proteomic profiling of PA, residual PA, and CXPA, and seven were proposed as protein signatures, some of which may be associated with the malignant phenotype acquisition.
Keyphrases
  • protein protein
  • small molecule
  • mass spectrometry
  • amino acid
  • label free
  • binding protein
  • high throughput
  • single cell
  • genome wide
  • risk assessment