Safety of Sodium-Glucose Cotransporter-2 Inhibitors in Patients with CKD and Type 2 Diabetes: Population-Based US Cohort Study.

Edouard L Fu Elvira D'Andrea Deborah J WexlerElisabetta PatornoJulie M Paik

Published in: Clinical journal of the American Society of Nephrology : CJASN (2023)

In U.S. patients with CKD and type 2 diabetes receiving routine care, SGLT2i use is associated with higher risks of genital infections, and potentially lower limb amputations and non-vertebral fractures.

Keyphrases

type diabetes
lower limb
chronic kidney disease
glycemic control
healthcare
cardiovascular disease
palliative care
insulin resistance
clinical practice
quality improvement
bone mineral density
human health
adipose tissue
risk assessment
metabolic syndrome
body composition
postmenopausal women