Skp2 modulates proliferation, senescence and tumorigenesis of glioma.
Juan WuHong-Kai SuZhi-Hui YuShao-Yan XiCheng-Cheng GuoZhe-Yu HuYue QuHai-Ping CaiYi-Ying ZhaoHua-Fu ZhaoFu-Rong ChenYu-Fan HuangShing-Shun Tony ToBing-Hong FengKe SaiZhong-Ping ChenJing WangPublished in: Cancer cell international (2020)
Our data demonstrated that Skp2 modulated glioma cell proliferation in vitro and in vivo, stem cell maintenance, and cell sensitivity to TMZ, which indicated that Skp2 could be a potential target for long-term treatment.