Nasal immune gene expression in response to azelastine and fluticasone propionate combination or monotherapy.
Annabelle M WattsNicholas P WestPeter K SmithPing ZhangAllan W CrippsAmanda J CoxPublished in: Immunity, inflammation and disease (2021)
AZE/FP, FP, and AZE had diverse effects on immune gene expression profiles in nasal mucosa samples. The moderate number of genes modulated by AZE/FP indicates alternative pathways in reducing AR symptoms whilst avoiding extensive local immune suppression.