Hypothalamus enlargement in mood disorders.

Stephanie SchindlerL SchmidtM StroskeM StorchAlfred AnwanderR TrampelM StraußU HegerlS GeyerP Schönknecht

Published in: Acta psychiatrica Scandinavica (2018)

Contrary to our expectations, the hypothalamus volume was increased in patients with uni- and bipolar affective disorders. The effect was left-sided and independent of medication status or statistical correction for covariates. Supported by emerging evidence that the stress response may be related to structural and functional asymmetry in the brain, our finding suggests a crucial role of the hypothalamus in mood disorders.

Keyphrases

bipolar disorder
sleep quality
healthcare
physical activity
adverse drug
brain injury
electronic health record