Microvascular endothelial dysfunction in skin is associated with higher risk of heart failure with preserved ejection fraction in women with type 2 diabetes: the Hoorn Diabetes Care System Cohort.
Elisa Dal CantoL van DeursenA G HoekP J M EldersH M den RuijterJ van der VeldenV van EmpelE H SernéE C EringaJ W J BeulensPublished in: Cardiovascular diabetology (2023)
Impaired microvascular responses to insulin and acetylcholine in skin confers a higher risk of HFpEF in women with type 2 diabetes. In vivo measures of systemic MVD could represent novel risk markers for HFpEF, opening new avenues for the prevention of HFpEF in type 2 diabetes.