Molecular Diagnosis of Monogenic Diabetes and Their Clinical/Laboratory Features in Turkish Children
Ruhsar Damla Gökşen ŞimşekEdiz YeşilkayaSamim ÖzenYılmaz KorErdal ErenÖzlem KorkmazMerih BerberoğluGülay KaragüzelEren ErAyhan AbaciSaadet Olcay EvliyaogluEmine Demet AkbaşEdip UnalSemih BoluÖzlem NalbantoğluAhmet AnikMeltem TayfunMuammer BüyükinanSaygın AbalıGulay Can YilmazDeniz KorElif SöbüZeynep ŞiklarRecep PolatŞükran DarcanPublished in: Journal of clinical research in pediatric endocrinology (2021)
Recent studies have indicated HNF1A-MODY is the most frequent of all the MODY-monogenic diabetes cases in the literature (50%), while GCK-MODY is the second most frequent (32%). In contrast to these reports, in our study, the most common form was GCK-MODY while less than 20% of cases were diagnosed with HNF1A-MODY.