Potential role of RAB6C-AS1 long noncoding RNA in different cancers.

Abbas Salavaty Fatemeh Movahedi MotlaghMehri BarabadiHamid CheshomiMohammad Javad Dehghan EsmatabadiMozhdeh ShahmoradiHamid Reza Soleimanpour-Lichaei

Published in: Journal of cellular physiology (2018)

We found that RAB6C-AS1 lncRNA is mostly overexpressed in GC. Also, based on bioinformatic and systems biology analyses, RAB6C-AS1 might function either as an oncogenic factor or tumor suppressor in a tissue-specific manner. Thus, RAB6C-AS1 could be considered as a candidate biomarker for various malignancies, especially prostate and brain cancers. According to our results, RAB6C-AS1 has a notable prognostic value for patients with brain lower grade glioma.

Keyphrases

long noncoding rna
prostate cancer
white matter
resting state
long non coding rna
functional connectivity
transcription factor
cerebral ischemia
multiple sclerosis
young adults
childhood cancer