Iron(II) Immobilized within a Metal-Organic Framework Mixed-Matrix Membrane as a H 2 O 2 Turn-On Sensor.
Yanping LiJiangpei YuanYu FangPublished in: Inorganic chemistry (2022)
H 2 O 2 detection is closely relevant to human health; however, most of the H 2 O 2 probes suffer from low accuracy and sensitivity because of the aggregating nature of solid sensors. In contrast, a mixed-matrix membrane (MMM) with high processability and flexibility is a suitable H 2 O 2 probe to overcome these drawbacks. Herein, we fabricated MOF-based MMMs by using a robust UiO-66-(COOH) 2 with carboxylate-chelating moieties, which were utilized for binding Fe (II) metal centers. The Fe (II)-immobilized MOF-MMM involved in a Fenton reaction when treated with H 2 O 2 , exhibiting a fluorescence turn-on property. Compared to the bulk-state MOF powder, the MOF-MMM sensor showed much-improved sensitivity (detection limit down to 0.0215 μM) because of the uniform dispersion of the probe and a sufficient contact with the analyte. This MOF-MMM sensor combinedly exhibited a turn-on fluorescence response and outstanding sensing properties with flexibility and processability, providing a novel platform suitable for practical sensing applications.
Keyphrases
- metal organic framework
- living cells
- fluorescent probe
- single molecule
- human health
- risk assessment
- sensitive detection
- loop mediated isothermal amplification
- small molecule
- climate change
- magnetic resonance
- computed tomography
- hydrogen peroxide
- nitric oxide
- label free
- energy transfer
- high throughput
- mass spectrometry
- transcription factor
- magnetic nanoparticles
- single cell