Effect of Growth Hormone Therapy in Patients with Noonan Syndrome: A Retrospective Study.

Louise Jayne ApperleyRenuka Ramakrishnan Poonam Dharmaraj Urmi Das Mohammed Didi Joanne C Blair Senthil Senniappan

Published in: International journal of endocrinology and metabolism (2020)

Our study has shown that growth hormone treatment significantly improves the height standard deviation score of patients with Noonan syndrome over a two-year course of growth hormone therapy without any side effects. Further research is required to analyse the long-term effect of growth hormone therapy in patients with Noonan syndrome, including the impact on final adult height.

Keyphrases

growth hormone
body mass index
case report
stem cells
mesenchymal stem cells
cell therapy