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Desialylation of O-glycans activates von Willebrand factor by destabilizing its autoinhibitory module.

Kayleigh M VoosWenpeng CaoNicholas A ArceEmily R LeganYingchun WangAsif ShajahanParastoo AzadiPete LollarXiaohui Frank ZhangRenhao Li
Published in: Journal of thrombosis and haemostasis : JTH (2021)
Desialylation of O-glycans around A1 increases its activity by destabilizing the AIM.
Keyphrases
  • cell surface