CERKL is upregulated in cutaneous squamous cell carcinoma and maintains cellular sphingolipids and resistance to oxidative stress.
J M MeyerE LeeA CelliKyungho ParkRaymond J ChoW LambertM PitchfordMitch GordonKenneth Y TsaiJ CleaverSarah T ArronTheodora M MauroPublished in: The British journal of dermatology (2021)
These findings suggest that CERKL may be important in cSCC progression and could lead to novel strategies for prevention and treatment of cSCC.