Differences in clinical significance of bronchodilator responses measured by forced expiratory volume in 1 second and forced vital capacity.

Joon Young ChoiSung Kyoung KimJin Hwa LeeKi-Suck JungKwang Ha YooKi-Eun HwangJong Deog LeeYu-Il KimHyoung Kyu YoonSoo-Jung Um

Published in: PloS one (2023)

In this study, BDR positive patients were more likely to be ever-smokers and to have worse symptoms and lung function than BDR negative patients. BDR-FVC was associated with worse symptom control and lung function compared to BDR-FEV1. However, there were no significant differences in exacerbation rate or decline in lung function in any BDR group. In addition, the effects of ICS on exacerbations were not significant in any group.

Keyphrases

lung function
chronic obstructive pulmonary disease
cystic fibrosis
air pollution
end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
prognostic factors
intensive care unit
depressive symptoms
smoking cessation
sleep quality
mechanical ventilation