Six-Month Follow-Up after Vaccination with BNT162b2: SARS-CoV-2 Antigen-Specific Cellular and Humoral Immune Responses in Hemodialysis Patients and Kidney Transplant Recipients.
Simone Cosima Boedecker-LipsAnja LautemStefan RunkelPascal KlimpkeDaniel KrausPhilipp KeilStefan HoltzVanessa TomallaPaul MarczynskiChristian Benedikt BoedeckerPeter Robert GalleMartina KochJulia Weinmann-MenkePublished in: Pathogens (Basel, Switzerland) (2022)
The humoral response rates to mRNA-based vaccination of HDPs are comparable to HCs, but antibody titers are lower. Furthermore, HDPs have weaker T-cell response to vaccination than HCs. KTRs have very low humoral and antigen-specific cellular response rates and antibody titers, which requires other vaccination strategies in addition to booster vaccination.