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Increased Frequency of Pfdhps A581G Mutation in Plasmodium falciparum Isolates from Gabonese HIV-Infected Individuals.

Jeanne Vanessa Koumba LengongoYaye Dié NdiayeMarie Louise Tshibola MbuyiJacques Mari Ndong NgomoDaouda NdiayeMarielle Karine Bouyou AkotetDenise Patricia Mawili-Mboumba
Published in: Malaria research and treatment (2019)
Pfdhps A581G mutation as well as new combination of quintuple mutations is found for the first time in isolates from HIV-infected patients in Gabon in comparison to a previous study. The detection of these genotypes at a nonnegligible frequency underlines the need of a regular surveillance of antifolates drug resistance.
Keyphrases
  • hiv infected patients
  • antiretroviral therapy
  • hiv infected
  • plasmodium falciparum
  • human immunodeficiency virus
  • public health
  • real time pcr