Polymorphisms of Mismatch Repair Pathway Genes Predict Clinical Outcomes in Oral Squamous Cell Carcinoma Patients Receiving Adjuvant Concurrent Chemoradiotherapy.

Thomas SenghoreWen-Chang WangHuei-Tzu ChienYou-Xin ChenChi-Kuang YoungShiang-Fu Huang Chih-Ching Yeh

Published in: Cancers (2019)

Our results indicated that the GG genotypes of MSH2 rs3732183 and MLH1 rs1800734 are associated with relatively high survival in OSCC patients treated using adjuvant CCRT. These polymorphisms may serve as prognosis predictors in OSCC patients.

Keyphrases

end stage renal disease
early stage
locally advanced
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
rectal cancer
squamous cell carcinoma
genome wide
radiation therapy
patient reported outcomes
dna methylation