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COVID-19 and Delayed Cerebral Ischemia-More in Common Than First Meets the Eye.

Pervinder BhogalHegoda Levansri Dilrukshan MakalandaAmeer E HassanDave FiorellaTommy AnderssonMuhammad AhmadHansjörg BäznerOunali JafferHans Henkes
Published in: Journal of clinical medicine (2021)
Since the arrival of the global COVID-19 pandemic scientists around the world have been working to understand the pathological mechanisms resulting from infection. There has gradually been an understanding that COVID-19 triggers a widespread endotheliopathy and that this can result in a widespread thrombosis and in particular a microthrombosis. The mechanisms involved in the microthrombosis are not confined to infection and there is evidence that patients with aneurysmal sub-arachnoid haemorrhage (SAH) also suffer from an endotheliopathy and microthrombosis. In this article we attempt to shed light on similarities in the underlying processes involved in both diseases and suggest potential treatment options.
Keyphrases
  • cerebral ischemia
  • coronavirus disease
  • sars cov
  • subarachnoid hemorrhage
  • blood brain barrier
  • brain injury
  • respiratory syndrome coronavirus