Cerebral cavernous malformations: Prevalence of cardiovascular comorbidities and allergic diseases compared to the normal population.
Philipp DammannDino Vitali SabanAnnika HertenBixia ChenYuan ZhuAlejandro SantosLaurèl RauschenbachKarsten Henning WredeRamazan JabbarliBörge SchmidtKarl-Heinz JöckelChristoph KleinschnitzMichael ForstingUlrich SurePublished in: European journal of neurology (2021)
We present novel data on CCM using a large single-institution and population-based setup. The study elaborates disease characteristics of CCM patients in detail. For the first time, evidence for an unexplained high prevalence of allergic diseases in this patient population is described (differing between sporadic and familial cases), supporting the hypothesis that immune response is involved in the pathogenesis of CCM.
Keyphrases
- immune response
- end stage renal disease
- newly diagnosed
- ejection fraction
- chronic kidney disease
- peritoneal dialysis
- prognostic factors
- late onset
- risk factors
- case report
- subarachnoid hemorrhage
- electronic health record
- allergic rhinitis
- big data
- dendritic cells
- amyotrophic lateral sclerosis
- atopic dermatitis
- inflammatory response
- patient reported