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Joint Effect of Multiple Prothrombotic Genotypes and Obesity on the Risk of Incident Venous Thromboembolism.

Tobias FrischmuthKristian HindbergMaiken E GabrielsenBen BrumptonKristian HveemSigrid K BrækkanJohn-Bjarne HansenVânia M Morelli
Published in: Thrombosis and haemostasis (2021)
 Our findings indicate that the combination of obesity and GRS has an additive effect on the risk of overall VTE. However, it may have a supra-additive effect on the risk of DVT and unprovoked VTE.
Keyphrases
  • venous thromboembolism
  • direct oral anticoagulants
  • insulin resistance
  • metabolic syndrome
  • weight loss
  • type diabetes
  • weight gain
  • cardiovascular disease
  • high fat diet induced
  • skeletal muscle