Login / Signup

ESKEMAP: exact sketch-based read mapping.

Tizian SchulzPaul Medvedev
Published in: Algorithms for molecular biology : AMB (2024)
-mers from the pattern sketch occur in the sketch of the text. We evaluate our algorithm's performance in mapping long reads to the T2T assembly of human chromosome Y, where ampliconic regions make it desirable to find all good mapping positions. For an equivalent level of precision as minimap2, the recall of our algorithm is 0.88, compared to only 0.76 of minimap2.
Keyphrases
  • high resolution
  • machine learning
  • high density
  • deep learning
  • endothelial cells
  • sars cov
  • single molecule
  • copy number
  • density functional theory
  • dna methylation