Serologic responses to the PfEMP1 DBL-CIDR head structure may be a better indicator of malaria exposure than those to the DBL-α tag.
Emily M StuckeAmadou NiangalyAndrea A BerryJason A BaileyDrissa CoulibalyAmed OuattaraKirsten E LykeMatthew B LaurensAntoine DaraMatthew AdamsJozelyn PabloAlgis JasinskasRie NakajimaAlbert E ZhouSonia AgrawalDeAnna J Friedman-KlabanoffShannon Takala-HarrisonBourema KouribaAbdoulaye K KoneJ Alexandra RoweOgobara K DoumboPhilip L FelgnerMahamadou A TheraChristopher V PloweMark A TravassosPublished in: Malaria journal (2019)
Larger PfEMP1 domains may be better indicators of malaria exposure than short, variable PfEMP1 fragments such as DBL-α tags. PfEMP1 head structures that include conserved sequences appear particularly well suited for study as serologic predictors of malaria exposure.