Blood-Brain Barrier Breakdown is a Sensitive Biomarker of Cognitive and Language Impairment in Patients with White Matter Hyperintensities.

Xing WangYulu ShiYiyi ChenYing GaoTingting WangZhengyang LiYi-Long Wang

Published in: Neurology and therapy (2023)

BBB impairment might be a more sensitive indicator for cognitive and language dysfunction than WMH volume in patients with WMH and possibly explains the heterogeneity of cognitive performance in patients with similar WMH burden.

Keyphrases

blood brain barrier
white matter
autism spectrum disorder
cerebral ischemia
oxidative stress
single cell
multiple sclerosis
risk factors