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Diagnostic Approaches to Investigate JAK2-Unmutated Erythrocytosis Based on a Single Tertiary Center Experience.

Young Eun LeeSoo Hyun SeoJinho KimSang-A KimJi Yun LeeJeong Ok LeeSoo-Mee BangKyoung Un ParkSang Mee Hwang
Published in: Molecular diagnosis & therapy (2024)
Somatic and germline mutations were identified in 36.4% and 33.3 % of the JAK2-unmutated group; most variants had unknown clinical significance. Not all genetic causes have been identified; comprehensive diagnostic approaches are crucial for identifying the cause of erythrocytosis.
Keyphrases
  • copy number
  • genome wide
  • dna repair
  • dna methylation
  • oxidative stress