Connecting the dots between different networks: miRNAs associated with bladder cancer risk and progression.
Cornelia BraicuRares BuigaRoxana CojocneanuMihail BuseLajos RadulyLaura Ancuta PopSergiu ChiraLiviuta BudisanAncuta JurjCristina CiocanLorand MagdoAlexandru IrimieFlorentin DobrotaBogdan PetrutIoana Berindan-NeagoePublished in: Journal of experimental & clinical cancer research : CR (2019)
This study thereby incorporates miRNAs as critical players in bladder cancer prognosis, where their altered gene expression profiles have a critical biological function in relationship with tumor molecular phenotype. The miRNA-mRNA regulatory networks identified in BC are ripe for exploitation as biomarkers or targeted therapeutic strategies.