Zebrafish model of RERE syndrome recapitulates key ophthalmic defects that are rescued by small molecule inhibitor of shh signaling.
Aman GeorgeJerry LeeJames LiuSuzie KimBrian P BrooksPublished in: Developmental dynamics : an official publication of the American Association of Anatomists (2022)
Zebrafish rerea mutants exhibit optic stalk and optic fissure closure defects. The optic fissure closure defect was rescued by an shh signaling inhibitor, suggesting that this defect could arise due to deregulated shh signaling. This article is protected by copyright. All rights reserved.