Antiphospholipid antibodies and the risk of adverse pregnancy outcomes in patients with systemic lupus erythematosus: a systematic review and meta-analysis.

Jinge HuangQingmiao ZhuBaizhou WangHanzheng WangZhijun XieXingyu ZhuTing ZhaoZi Yang

Published in: Expert review of clinical immunology (2024)

Both LA and aCL were risk factors of APOs in patients with SLE. Not only ACL, particularly aCL-IgM, but antiβ2GP1 were associated with an increased risk of fetal loss, while LA appeared to indicate the risk of preterm birth.PROSPERO (CRD42023388122).

Keyphrases

preterm birth
pregnancy outcomes
systemic lupus erythematosus
risk factors
low birth weight
pregnant women
gestational age
disease activity
emergency department