First experiences with dynamic renal [ 68 Ga]Ga-DOTA PET/CT: a comparison to renal scintigraphy and compartmental modelling to non-invasively estimate the glomerular filtration rate.

David KerstingMiriam SraiebRobert SeifertPedro Fragoso CostaSandra KazekLukas KesslerLale UmutluWolfgang Peter FendlerWalter JentzenKen HerrmannFlorian BütherMichael NaderChristoph Rischpler

Published in: European journal of nuclear medicine and molecular imaging (2022)

Ga]Ga-DOTA PET can be a suitable alternative to conventional scintigraphy. Visual assessment of PET images and conventional renograms revealed comparable results. GFR values derived by non-invasive single-compartmental-modelling of PET data show a good correlation to serum creatinine-derived GFR values. In patients with undisturbed urinary efflux, the correlation was excellent. Dynamic PET data acquisition for 15 min is sufficient for visual evaluation and GFR derivation.

Keyphrases

pet ct
positron emission tomography
electronic health record
big data
mental health
deep learning
computed tomography
uric acid