Loss of SMAD4 Promotes Colorectal Cancer Progression by Recruiting Tumor-Associated Neutrophils via the CXCL1/8-CXCR2 Axis.
Ryotaro OgawaTakamasa YamamotoHideyo HiraiKeita HanadaYoshiyuki KiyasuGen NishikawaRei MizunoSusumu InamotoYoshiro ItataniYoshiharu SakaiKenji KawadaPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2019)
Blockade of the CXCL1/8-CXCR2 axis could be a novel therapeutic approach against SMAD4-negative colorectal cancer.