Higher versus lower positive end-expiratory pressure in patients without acute respiratory distress syndrome: a meta-analysis of randomized controlled trials.
Tommaso PettenuzzoAnnalisa BoscoloAlessandro De CassaiNicolò SellaFrancesco ZarantonelloPaolo PersonaLaura PasinGiovanni LandoniPaolo NavalesiPublished in: Critical care (London, England) (2021)
In our meta-analysis of RCTs, higher PEEP, compared with lower PEEP, was not associated with mortality in patients without ARDS receiving invasive mechanical ventilation. Further large high-quality RCTs are required to confirm these findings.
Keyphrases
- acute respiratory distress syndrome
- mechanical ventilation
- end stage renal disease
- extracorporeal membrane oxygenation
- newly diagnosed
- ejection fraction
- chronic kidney disease
- intensive care unit
- peritoneal dialysis
- systematic review
- prognostic factors
- type diabetes
- coronary artery disease
- risk factors
- respiratory failure
- cardiovascular events