An Artificial Placenta Experimental System in Sheep: Critical Issues for Successful Transition and Survival up to One Week.
Elisenda EixarchMiriam IllaRaquel FuchoKambiz RezaeiAmeth Hawkins-VillarrealSara Bobillo-PerezPaula Cecilia RandanneMiguel MoranMarina ChordaSergio Sanchez-MartinezJolanda J D de RooMaria Del Mar VelillaRuth Del RioMarc GallegoDaniel Sanin-RamirezVictor NarvaezFàtima CrispiElisenda Bonet-CarneEduard GratacosPublished in: Biomedicines (2023)
Achieving a reproducible experimental setting for an AP system is extremely challenging, time- and effort-consuming, and requires a highly multidisciplinary team. As a result of the learning curve, we achieved reproducible transition and survival up to 7 days. Extended survival requires improving instrumentation with custom-designed devices.