Immune Checkpoint Blockade for Metastatic Uveal Melanoma: Patterns of Response and Survival According to the Presence of Hepatic and Extrahepatic Metastasis.
Elias A T KochAnne PetzoldAnja WesselyEdgar DippelAnja GesierichRalf GutzmerJessica C HasselSebastian HaferkampBettina HohbergerKatharina C KählerHarald KnorrNicole KreuzbergUlrike LeiterCarmen LoquaiFriedegund MeierMarkus MeissnerPeter MohrClaudia PföhlerFarnaz RahimiDirk SchadendorfBeatrice SchellMax SchlaakPatrick TerheydenKai-Martin ThomsBeatrice Schuler-ThurnerSelma UgurelJens UlrichJochen Sven UtikalMichael WeichenthalFabian ZillerCarola BerkingMarkus Vincent Hepptnull On Behalf Of The German Dermatologic Cooperative Oncology Group DeCOG Committee Ocular MelanomaPublished in: Cancers (2021)
The survival of this large cohort of patients with advanced UM was more favorable than reported in previous benchmark studies. Patients with both hepatic and extrahepatic metastasis showed more favorable survival and higher response to dual ICB than those with hepatic metastasis only.