Body Mass Index and Weight Loss in Metastatic Colorectal Cancer in CALGB (Alliance)/SWOG 80405.
Brendan J GuercioSui ZhangAlan P VenookFang-Shu OuDonna NiedzwieckiHeinz-Josef LenzFederico InnocentiBrian C MullenBert H O'NeilJames E ShawBlase N PoliteHoward S HochsterJames N AtkinsRichard M GoldbergJustin C BrownEileen M O'ReillyRobert J MayerCharles David BlankeCharles S FuchsJeffrey A MeyerhardtPublished in: JNCI cancer spectrum (2020)
In this prospective study of patients with mCRC, BMI at time of first-line chemotherapy initiation was not associated with patient outcome. Weight loss prior to study entry was associated with increased risk of patient mortality and disease progression.