Evaluation of the peripheral blood T and B cell subsets and IRF-7 variants in adult patients with severe influenza virus infection.

Nursel Calik Basaran Çağman Tan Lale Özışık Begüm Özbek Ahmet Çagkan Inkaya Şehnaz Alp Ebru Ortaç Ersoy Deniz Çağdaş Ayvazİlhan Tezcan

Published in: Health science reports (2022)

The increases in central and effector memory Th, central memory CTL and decrease of naive CTLs may be secondary to the virus infection. K179E (rs1061502) and H195L (rs139709725) variants were not reported to be related with susceptibility to an infection yet. It is conceivable to investigate for novel variants in other genes related to antiviral immunity.

Keyphrases

peripheral blood
copy number
dendritic cells
working memory
genome wide
regulatory t cells
hiv infected
early onset
drug induced
immune response