Visceral obesity is associated with an increased risk of developing esophago-gastric junctional adenocarcinoma in Japan: a population-based case-control study in Akita Prefecture.

Kenta WatanabeShigeto KoizumiKenji ShiraneHidehiko TsudaHiroyuki WatanabeTsuyotoshi TsujiKengo OnochiKiyonori YamaiChika KusanoTakahiro DohmenYohei HorikawaTakuma AjimineMasahiro SaitoTomoyuki KoikeAtsushi MasamuneYosuke ShimodairaTamotsu MatsuhashiKatsunori Iijima

Published in: Esophagus : official journal of the Japan Esophageal Society (2022)

We found paradoxical associations between EGJACs and obesity-related parameters (BMI vs. VFA) in a Japanese population, suggesting a potentially pivotal role of the VFA rather than the BMI as a risk factor for EGJACs.

Keyphrases

weight gain
insulin resistance
metabolic syndrome
body mass index
weight loss
high fat diet induced
type diabetes
squamous cell carcinoma
adipose tissue
radiation therapy
locally advanced