Comparison of combined intravenous and intra-arterial thrombolysis with intravenous thrombolysis alone in stroke patients undergoing mechanical thrombectomy: a propensity-matched analysis.
Sameh Samir ElawadyRahim Abo KasemBhageeradh MulpurConor CunninghamHidetoshi MatsukawaMohammad Mahdi SowlatAtakan OrscelikNoah L A NawabiJulio IsidorIlko L MaierPascal M JabbourJoon-Tae KimStacey Quintero WolfeAnsaar RaiRobert M StarkeMarios-Nikos PsychogiosEdgar A SamaniegoShinichi YoshimuraHugo H Cuellar-SaenzBrian M HowardAli AlawiehAli AlarajMohamad EzzeldinDaniele G RomanoOmar TanweerJustin R MascitelliIsabel R FragataAdam J PolifkaFazeel SiddiquiJoshua W OsbunRamesh GrandhiRoberto Javier CrosaCharles C MatoukMin S ParkBrinjikji WMark MossErgun DagliogluRichard WilliamsonPedro Navia-ÁlvarezPeter T KanReade Andrew De LeacyShakeel A ChowdhryDavid J AltschulAlejandro M SpiottaMichael R LevittNitin GoyalPublished in: Journal of neurointerventional surgery (2024)
The combined use of IAT and IVT thrombolysis in AIS-LVO patients undergoing MT is safe. Although the MT+IVT+ IAT group demonstrated lower rates of recanalization and early neurological improvement, long-term functional outcomes were favorable in this group suggesting a potential delayed benefit of IAT.