Serum apelin-12 and obesity-related markers in Egyptian children with Down syndrome.
Sohier YahiaNanees Abdel-Badie SalemAmany El-HawaryMohamed SalemReham M El-FarahatyAbd El-Hady El-GilanyRasha M S ShoaibMohamed Ahmed NoureldinPublished in: European journal of pediatrics (2023)
• Higher serum apelin-12 was observed in obese-DS and obese-DS with MetS than obese-control and obese-control with MetS respectively. The increase in apelin-12 level with increasing obesity grades was more pronounced in obese-DS. • Apelin-12 strongly correlated with obesity-related markers and MetS components in obese-DS. Apelin-12 performed better as a diagnostic biomarker for MetS in obese-DS than obese-control.